Cancer is the major lethal disease all around the world, despite huge progress in the understanding, treatment and prevention, the oncology diseases remain leading mortality-rate reason in the well-developed countries. Since FTIR- spectroscopy can distinguish normal and tumor cells as well as different levels of malignancy, in principle can be calculated the dissemination level of tumor premalignant status through biopsy in definite space of tumor heart and to be analyzed resection frames for individual patient. Exact tumor/ premalignant classification are significant for successful therapy determination, where incorrect definition can lead to wrong prognosis. Infrared spectroscopy is a potentially new method for cancer diagnosis, due to the sensitivity of the technique to alterations in cellular biochemistry which accompany disease stages. Infrared radiation is absorbed by tissues, fluids and cells to promote vibration of the covalent bonds of molecules within the sample. The wavelength of infrared radiation which is absorbed depends upon the nature of the covalent bond and the strength of any intermolecular interactions. The infrared spectrum of a sample is therefore a biochemical fingerprint. As the biochemistry of cells, tissues and fluids must change during disease (there can be no disease without abnormal biochemistry) then the biochemical fingerprint of the cells, tissues and fluids should be altered when a disease is present.
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